FIELD: chemistry.
SUBSTANCE: invention concerns novel compounds of formula I: , where M is macrolide subunit of substructure II:
, L is chain of substructure III: -X1-(CH2)m-Q-(CH2)n-X2-, D is steroid or non-steroid subunit derived from steroid or non-steroid NSAID medicines (nonsteroid anti-inflammatory drug) with anti-inflammatory effect; pharmaceutically acceptable salts and solvates of claimed compounds; methods and intermediary compounds for obtainment of claimed compounds.
EFFECT: improved therapeutic effect, application in inflammatory disease and state treatment for humans and animals.
37 cl, 18 ex
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Authors
Dates
2009-05-20—Published
2004-04-23—Filed