MACROLIDE CONJUGATES WITH ANTIINFLAMMATORY EFFECT Russian patent published in 2009 - IPC C07J1/00 C07D413/12 C07D273/01 

Abstract RU 2355699 C2

FIELD: chemistry.

SUBSTANCE: invention concerns novel compounds of formula I: , where M is macrolide subunit of substructure II: , L is chain of substructure III: -X1-(CH2)m-Q-(CH2)n-X2-, D is steroid or non-steroid subunit derived from steroid or non-steroid NSAID medicines (nonsteroid anti-inflammatory drug) with anti-inflammatory effect; pharmaceutically acceptable salts and solvates of claimed compounds; methods and intermediary compounds for obtainment of claimed compounds.

EFFECT: improved therapeutic effect, application in inflammatory disease and state treatment for humans and animals.

37 cl, 18 ex

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RU 2 355 699 C2

Authors

Mersep Mladen

Mesik Milan

Tomaskovits Linda

Markovits Stribor

Khrvasits Boska

Makarukha Stedzhik Oresta

Polzhak Visnja

Dates

2009-05-20Published

2004-04-23Filed