FIELD: pharmacology.
SUBSTANCE: described are novel derivatives of triazole of general formulas (I) 
or (II) 
or their pharmaceutically acceptable salts, where R1 represents H, C1-C6-alkyl, or group CONRaRb, Ra represents hydrogen or C1-C6-alkyl; R2 represents H or C1-C6-alkyl; R3 represents H or F, CI, Br or I; R4 represents H; R5 represents CF3 or O-(C1-C4)alkyl, three times substituted with F; R6 and R7 each independently represents H, F or CF3, on condition that one of R6 and R7 always represents H.
EFFECT: application of said compounds for preparing medication for treatment and prevention of pain or pain-induced disturbances; pharmaceutical composition containing novel compounds, and method of their obtaining.
9 cl, 20 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SUBSTITUTED TRIAZOLES AS SODIUM CHANNEL BLOCKERS | 2004 |
|
RU2372339C2 |
| SPIROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION AND USE | 2018 |
|
RU2781639C2 |
| CATECHOL-O-METHYL TRANSFERASE INHIBITORS AND USE THEREOF IN TREATING PSYCHOTIC DISORDERS | 2011 |
|
RU2586974C2 |
| TRICYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USING THEM FOR TREATING IMMUNOLOGICAL AND ONCOLOGICAL COMPOUNDS | 2009 |
|
RU2545023C9 |
| TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS | 2009 |
|
RU2561104C2 |
| PYRIMIDINE DERIVATIVES AND USE THEREOF IN TREATING RESPIRATORY DISEASES, SUCH AS COPD | 2011 |
|
RU2604719C2 |
| INHIBITOR COMPOUNDS | 2013 |
|
RU2673079C2 |
| DERIVATIVES OF 1,2,4-TRIAZOLE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 2003 |
|
RU2319703C2 |
| AKT ACTIVITY INHIBITORS | 2006 |
|
RU2421454C2 |
| ARYLSULFONYLMETHYL OR ARYLSULFONAMIDE DERIVATIVES OF AROMATICS, PHARMACEUTICAL COMPOSITION BASED ON THEM AND WAY OF TREATMENT AGAINST ABNORMALITIES RESPONSIVE TO DOPAMINE D RECEPTOR LIGAND TREATMENT, WITH THEIR HELP | 2005 |
|
RU2442781C2 |
