FIELD: pharmacology.
SUBSTANCE: invention relates to pharmacon immediately dealing with preparation of a solid medication for treatment of diabetes and its sequela. The medication contains metformin or a salt thereof, pioglitazone or a salt thereof, homogenously dispersed, as well as target admixtures. The ratio of the average particle size of metformin or the salt thereof to the average particle size of pioglitazone or the salt thereof varies from 2.23:1 to 8.06:1.
EFFECT: provision for high homogeneity and dissolution degree of the active ingredient.
5 cl, 3 tbl, 14 ex
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Authors
Dates
2009-06-10—Published
2003-10-06—Filed