METHOD FOR CONSERVATIVE TREATMENT IN PATIENTS AT NONOPERABLE PULMONARY CARCINOMA Russian patent published in 2007 - IPC A61K35/28 A61N5/10 A61K31/282 A61K31/675 A61K31/704 A61P35/00 A61M1/36 

FIELD: medicine, oncology.

SUBSTANCE: the present innovation deals with treating patients at not small cell nonoperable pulmonary carcinoma. It is necessary to introduce chemopreparations incubated with a patient's body automedium and carry out radiation therapy. Moreover, medullary iliac suspension should be incubated with chemopreparations in a thermostat at 37°C for 30 min and reinfused for a patient intravenously by drop technique. In 2 wk one should carry out radiation therapy at the mode of accelerated hyperfractioning per 1.3 Gy per 2 fractions daily at a 4-h-long interval between fractions during 2 wk daily. It is important to carry out 3 such cycles that combine the introduction of chemopreparations upon medullary suspension and radiation therapy, at a 2-wk-long interval, the difference being in the mode of radiation therapy only. So, in the course of the second cycle a single dosage of irradiation corresponds to 1.2 Gy twice daily at a 4-h-long interval during 2 wk. During the third cycle - per 1.1 Gy daily at a 4-h-long interval for 2 wk. The innovation enables to improve final results and quality of life in such patients; decrease side manifestations of anti-tumor therapy at inspecific stimulation of immune status with the elements of medullary suspension.

EFFECT: higher efficiency of therapy.

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