FIELD: chemistry.
SUBSTANCE: m-chlorobenzophenone is used as an intermediate product in synthesis of original anticonvulsant "halodif" (m-chlorobenzhydrylurea). The method involves diazotisation of 2-amino-5-chlorobenzophenone at room temperature using p-toluenesulfonic acid and polymer diazotising agent, with subsequent treatment of the obtained diazonium tosylate with an aqueous solution of sodium hypophosphite.
EFFECT: method allows for obtaining target product with quantitative output.
6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF OBTAINING META-CHLOROBENZOPHENONE AS HALF-PRODUCT OF ANTICONVULSIVE MEDICATION "HALODIF" | 2012 |
|
RU2510638C1 |
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|
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| METHOD FOR PRODUCTION OF 2-AMINO-5-CHLOROBENZHYDROL, 2-N-METHYLAMINO-5-CHLORBENZHYDROL AND M-CHLOROBENZHYDROL | 1992 |
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| METHOD OF PRODUCING SUBSTITUTED AROMATIC COMPOUNDS | 2015 |
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| METHOD OF OBTAINING META-CHLOROBENZHYDRYLUREA(HALODIF) WITH APPLICATION OF MAGNETIC NANOPARTICLES, MODIFIED WITH SULPHOGROUPS | 2014 |
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| PROCESS FOR PREPARING AZO-DYES FOR PROTEIN FIBERS | 0 |
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| METHOD OF PRODUCING MONO- OR DISAZO DYES BASED ON METHYL PHLOROGLUCINOL | 2008 |
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