FIELD: medicine; pharmaceutics.
SUBSTANCE: preparation includs methylnaltrexone or its salt and a chelating agent. The preparation represents a solution which has pH from 2 to 6. The chelating agent is ethylenediaminetetraacetic acid or its derivative.
EFFECT: decomposing prevention of methylnaltrexone or its salts and stability of a methylnaltrexone preparation in the form of a solution after storage within 12 months.
10 cl, 3 dwg, 7 ex
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Authors
Dates
2009-07-27—Published
2004-04-08—Filed