FIELD: medicine.
SUBSTANCE: present invention relates medicine and concerns delivery of osteogene proteins using injection in the form of a firm hinge. The compositions contain a calcium-phosphatic material, osteogene protein, and unessential additives, for example, such as a bone resorption inhibitor. Ways of preparation of pharmaceutical compositions and ways of application of osteogene compositions for treatment of defects of a bone are also described. The invention provides decrease of osteoporosis severity and amount of osteoporotic lesions, healing of fractures, restoration of cartilages, healing of defects non-union and artificial ankylosis, stimulation of growth of bones.
EFFECT: decrease of osteoporosis severity and amount of osteoporotic lesions, healing of fractures, restoration of cartilages, healing of defects non-union and artificial ankylosis, stimulation of growth of bones.
28 cl, 6 ex, 2 dwg
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