FIELD: medicine.
SUBSTANCE: invention relates medicine and concerns the pharmaceutical composition suitable for parenteral introduction, containing Nε-(γ-L-glutamyl)-L-lysine peptide of the general formula: H-Lys(H-Glu-OH)-OH, stimulating angiogenesis which can be used as a medical product for correction of angiogenesis disturbances. The invention provides intensifying of expression of a vascular endothelial growth factor gene, stimulation of metabolic activity, proliferation and migration of endotheliocytes, normalisation of cytokines production.
EFFECT: intensification of expression of a vascular endothelial growth factor gene, stimulation of metabolic activity, proliferation and migration of endotheliocytes, normalisation of cytokines production.
5 cl, 7 ex, 3 dwg, 6 tbl
Title |
Year |
Author |
Number |
PEPTIDE ENHANCING RESISTANCE OF CAPILLARIES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS USING |
2006 |
- Khavinson Vladimir Khatskelevich
- Grigor'Ev Evgenij Iosifovich
- Malinin Vladimir Viktorovich
- Ryzhak Galina Anatol'Evna
|
RU2295970C1 |
PHARMACEUTICAL COMPOSITION CONTAINING AS AN ACTIVE INGREDIENT A FUSED PROTEIN IN WHICH A TUMOR-PENETRATING PEPTIDE AND AN ANTIANGIOGENIC AGENT ARE FUSED FOR PREVENTING AND TREATING CANCER OR ANGIOGENESIS-RELATED DISEASES |
2016 |
- Kvon, Khiuk-Sang
- Ko, Dzong-Khi
- Li, Jong-Min
- Dzung, Khiej-Joon
- Yang, Seok-Voo
- Kang, Dzae-Khoon
- Kim, Jong-Sung
|
RU2727238C2 |
PEPTIDE COMPOUND, STIMULATING FUNCTION OF REPRODUCTIVE SYSTEM, PHARMACEUTICAL COMPOSITION AND METHOD OF APPLICATION |
2006 |
- Khavinson Vladimir Khatskelevich
- Grigor'Ev Evgenij Iosifovich
- Kudrjavtseva Tat'Jana Anatol'Evna
- Ryzhak Galina Anatol'Evna
|
RU2324703C1 |
PEPTIDE POSSESSING IMMUNOGEROPROTECTIVE EFFECT, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS USING |
2006 |
- Khavinson Vladimir Khatskelevich
- Grigor'Ev Evgenij Iosifovich
- Malinin Vladimir Viktorovich
- Ryzhak Galina Anatol'Evna
|
RU2301074C1 |
PEPTIDE POSSESSING STRESS-PROTECTING EFFECT, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS USING |
2006 |
- Khavinson Vladimir Khatskelevich
- Grigor'Ev Evgenij Iosifovich
- Malinin Vladimir Viktorovich
- Ryzhak Galina Anatol'Evna
|
RU2304444C1 |
AGENT INHIBITING ANGIOGENESIS IN VISUAL ORGAN DISEASE |
2001 |
- Khavinson V.Kh.
- Khokkanen V.M.
- Trofimova S.V.
- Malinin V.V.
|
RU2177801C1 |
PEPTIDE PHARMACEUTICAL COMPOSITION, BASED DRUG FOR GASTRODUODENAL DISEASES CAUSED BY HELICOBACTER PYLORI, AND METHOD OF USING IT |
2011 |
- Khavinson Vladimir Khatskelevich
- Kvetnoj Igor' Moiseevich
- Poljakova Viktorija Olegovna
- Ryzhak Galina Anatol'Evna
- Kozlov Lenar Vasil'Evich
|
RU2449805C1 |
PHARMACEUTICAL COMPOSITION ON BASIS OF PEPTIDE POSSESSING ANTITUMORAL ACTION |
2007 |
- Khavinson Vladimir Khatskelevich
- Ryzhak Galina Anatol'Evna
- Kozlov Lenar Vasil'Evich
|
RU2362579C1 |
TETRAPEPTIDE STIMULATING FUNCTIONAL ACTIVITY OF HEPATOCYTES, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD OF ITS USE |
2000 |
|
RU2166957C1 |
PEPTIDE WITH NEUROSTIMULATION ACTIVITY AND RESTORE LEARNING AND MEMORY FORMATION, PHARMACEUTICAL COMPOSITION ON ITS BASIS AND METHOD FOR ITS APPLICATION |
2021 |
- Khavinson Vladimir Khatskelevich
- Ryzhak Galina Anatolevna
- Linkova Natalya Sergeevna
- Mironova Ekaterina Sergeevna
|
RU2768475C1 |