PHARMACEUTICAL COMPOSITION BASED ON PEPTIDE REGULATING DISTURBANCES OF ANGIOGENESIS, AND WAY OF ITS APPLICATION Russian patent published in 2009 - IPC A61K38/02 A61P9/10 

Abstract RU 2363488 C1

FIELD: medicine.

SUBSTANCE: invention relates medicine and concerns the pharmaceutical composition suitable for parenteral introduction, containing Nε-(γ-L-glutamyl)-L-lysine peptide of the general formula: H-Lys(H-Glu-OH)-OH, stimulating angiogenesis which can be used as a medical product for correction of angiogenesis disturbances. The invention provides intensifying of expression of a vascular endothelial growth factor gene, stimulation of metabolic activity, proliferation and migration of endotheliocytes, normalisation of cytokines production.

EFFECT: intensification of expression of a vascular endothelial growth factor gene, stimulation of metabolic activity, proliferation and migration of endotheliocytes, normalisation of cytokines production.

5 cl, 7 ex, 3 dwg, 6 tbl

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RU 2 363 488 C1

Authors

Khavinson Vladimir Khatskelevich

Grigor'Ev Evgenij Iosifovich

Malinin Vladimir Viktorovich

Ryzhak Galina Anatol'Evna

Kozlov Lenar Vasil'Evich

Dates

2009-08-10Published

2007-11-26Filed