RISK-BASED APPROACH TO UNFAVOURABLE CLINICAL COURSE OF SEVERE ACUTE TOXIC EXPOSURE OF PSYCHOTROPICS Russian patent published in 2009 - IPC G01N33/50 

Abstract RU 2364869 C1

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely toxicology. There is disclosed risk-based approach to unfavourable clinical course of severe toxic exposure of psychotropics. Biophysical studies aim at conformational alterations of albumin by calculating a fluorescence quenching constant. Unfavourable clinical outcome is predicted, if the quenching constant is lower than 1.0 l/mol. The approach allows for on-time estimate of the patient's condition to carry out adequate therapeutic action.

EFFECT: possibility for on-time estimate of the patient's condition to carry out adequate therapeutic action.

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RU 2 364 869 C1

Authors

Syromjatnikova Elena Davydovna

Dobretsov Gennadij Evgen'Evich

Gryzunov Jurij Anatol'Evich

Il'Jashenko Kapitolina Konstantinovna

Dates

2009-08-20Published

2008-01-22Filed