FIELD: medicine.
SUBSTANCE: invention concerns medicine, namely toxicology. There is disclosed risk-based approach to unfavourable clinical course of severe toxic exposure of psychotropics. Biophysical studies aim at conformational alterations of albumin by calculating a fluorescence quenching constant. Unfavourable clinical outcome is predicted, if the quenching constant is lower than 1.0 l/mol. The approach allows for on-time estimate of the patient's condition to carry out adequate therapeutic action.
EFFECT: possibility for on-time estimate of the patient's condition to carry out adequate therapeutic action.
3 ex
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Authors
Dates
2009-08-20—Published
2008-01-22—Filed