2,5-DISUBSTITUTED 3-MERCAPTOPENTANIC ACIDS AND METHOD OF OBTAINING THEM Russian patent published in 2009 - IPC C07D213/73 C07D221/22 C07D233/88 C07D401/06 C07D405/06 C07D409/06 A61P7/02 

FIELD: chemistry.

SUBSTANCE: described is compound representing 2,5-disubstituted 3-mercaptopentanic acid of formula (I) or its pharmaceutically acceptable salt, where R' represents phenyl, possibly substituted, naphtyl, pyridinyl, 1,2,3,4-tetrahydropyrimidine-2,4-dion-yl, substituted with C_1-4alkyl, or tetrahydrothienyl; R² represents aminopyridinyl, aminothiazolyl or 3-azabicyclo[3.2.1]octyl; R³ represents C_1-4alkoxy, possibly substituted with phenyl (substituted with halogen) or pyridinyl; NR⁵R⁶ or N-bonded 5- or 6-member heterocyclic ring representing pyrrolidinyl, piperidinyl or piperazinyl ring, non-substituted or monosubstituted, or condensed with benzene ring, which is possibly substituted with C_1-4alkoxy; R⁴ represents N-bonded pyrrolidinyl ring, monosubstituted with C_1-4alkyl, which is substituted with NHphenyl; R⁵ and R⁶ independently represent hydrogen, C_1-4alkyl, possibly substituted, or C_2-4alkenyl; and method of obtaining it.

EFFECT: obtaining compounds inhibiting carboxypeptidase and which can be used in prevention and treatment of diseases in which inhibiting carboxypeptidase is useful.

7 cl, 1 tbl, 53 ex