DIHYDROTETRABENAZENES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Russian patent published in 2009 - IPC C07D455/06 C07D471/04 C07D491/14 A61K31/473 A61P25/14 A61P25/24 

Abstract RU 2365590 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel 3,11b-cys-dihydrotetrabenazene of general formula (1) or to its antipode . Invention also relates to composition, to pharmaceutical composition, to application of 3,11b-cys-dihydrotetrabenazene, to method of obtaining 3,11b-cys-dihydrotetrabenazene by i. 1, to compounds of formula (II), (III), as well as to ester of Mosher's acid and 3,11b-cys-dihydrotetrabenazene.

EFFECT: obtaining novel biologically active compounds possessing activity as inhibitor of vesicular carrier of monoamines VMAT2.

23 cl, 12 ex, 8 tbl

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RU 2 365 590 C2

Authors

Tridzhett Robert

Klark Jan

Tertl Robert

Dzhonston Grant

Dates

2009-08-27Published

2005-02-11Filed