FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine; it is intended for the treatment of late dyskinesia in an individual. The individual is injected with a compound of (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline-2-yl complex ester of (S)-2-amino-3-methyl-butyric acid or its pharmaceutically acceptable salt in a daily dose of 40 mg or 80 mg per free base.
EFFECT: invention provides for Cmax from 15 ng to 60 ng of (+)α-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline-2-ol ((+)α-HTBZ) per ml of plasma during 8 hours.
21 cl, 1 dwg, 1 tbl, 2 ex
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