POLYMORPHIC MODIFICATION OF A IBANDRONATE Russian patent published in 2009 - IPC C07F9/38 A61K31/66 A61P19/08

Abstract RU 2368617 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a new crystalline polymorphic modification of a monohydrate of mon-sodium salt of 3-(N-methyl-N-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid (ibandronate) of formula 1, used for controlling hypercalcemia. formula 1.

EFFECT: obtaining a new crystalline modification of biologically active compound.

14 cl, 6 dwg, 7 ex

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RU 2 368 617 C2

Authors

Ajermann Uve

Jungkhans Bernd

Knipp Bernkhard

Zattel'Kau Tim

Dates

2009-09-27—Published

2006-01-24—Filed