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(19)

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2 434 845

(13)

(51)

IPC

C07C215/66(2006-01-01)

A61K31/14(2006-01-01)

A61P25/04(2006-01-01)

(21) (22)

Application

2008106455/04, 2006-07-20

(24)

Start date

2006-07-20

(22)

Actual filing date

2006-07-20

(45)

Published

2011-11-27

(72)

Inventor

Gruss Mikhaehl'Khell' Vol'FgangShelagevich MartinBergkhauzen JernDi-Pol S'Jusan MargaretFon-Raumer Markus

(73)

Holder

Grjunental' Gmbkh

3-[2-(DIMETHYLAMINO)METHYL-(CYCLOHEX-1-YL)]PHENOL MALEATE AND ITS CRYSTALLINE FORMS Russian patent published in 2011 - IPC C07C215/66 A61K31/14 A61P25/04

Abstract RU 2434845 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to 3-[2-(dimethylamino)methyl-(cyclohex-1-yl)]phenol maleate of formula in form of enantiomer with absolute configuration (1R, 2R), which possesses pain-killing action.

EFFECT: invention relates to methods of obtaining said maleate, including crystalline forms A and B, pharmaceutical composition and application of maleate of formula (i) for preparation of pharmaceutical composition, intended for treatment of pain states.

33 cl, 4 dwg, 4 tbl, 25 ex

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RU 2 434 845 C2

Authors

Gruss Mikhaehl'

Khell' Vol'Fgang

Shelagevich Martin

Bergkhauzen Jern

Di-Pol S'Jusan Margaret

Fon-Raumer Markus

Dates

2011-11-27—Published

2006-07-20—Filed