FIELD: medicine.
SUBSTANCE: immunogenic vaccine composition comprises macromolecular protein structure containing proteins of bird influenza virus HA, NA, and Ml and a carrier or dilution agent. The suggested group of inventions provides safety recombinant vaccine practice and highly immunogenic self-organised macromolecules integrated in plasmamembranes comprising multivariate replicas of structural protein of bird influenza virus demonstrating neutralising epitopes in native conformations.
EFFECT: invention can be used as vaccine to prevent influenza infection and as a chemical agent for virus researches and chemical recognition.
31 cl, 12 dwg, 2 tbl, 13 ex
Authors
Dates
2009-10-10—Published
2004-07-09—Filed