FIELD: medicine.
SUBSTANCE: invention concerns medicine, particularly endocrinology and anesthesiology, and can be applied in pre-operation preparation of pheochromocytoma cases. It involves peroral administration of doxazozin drug in 14-21 day before operation. Initial daily drug dosage is 4 mg, by 2 mg twice per day, with further dosage increase by 2-4 mg till arterial pressure is normalised. Maximum dosage is 16 mg per day. After arterial pressure stabilisation daily doxazozin administration continues in determined therapeutic dosage. Last doxazozin take is performed in 90 minutes before narcosis in dosage of 8-12 mg.
EFFECT: prevented hypertensive crisis caused by hypercatecholaminemia during the whole operation due to timely maintenance of selective al-adrenoreceptor blockade.
1 tbl, 1 ex
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Authors
Dates
2009-10-27—Published
2008-03-28—Filed