METHOD OF PRE-OPERATION PREPARATION OF PHEOCHROMOCYTOMA CASE Russian patent published in 2009 - IPC A61K31/496 A61P9/12 A61P43/00 

Abstract RU 2371178 C1

FIELD: medicine.

SUBSTANCE: invention concerns medicine, particularly endocrinology and anesthesiology, and can be applied in pre-operation preparation of pheochromocytoma cases. It involves peroral administration of doxazozin drug in 14-21 day before operation. Initial daily drug dosage is 4 mg, by 2 mg twice per day, with further dosage increase by 2-4 mg till arterial pressure is normalised. Maximum dosage is 16 mg per day. After arterial pressure stabilisation daily doxazozin administration continues in determined therapeutic dosage. Last doxazozin take is performed in 90 minutes before narcosis in dosage of 8-12 mg.

EFFECT: prevented hypertensive crisis caused by hypercatecholaminemia during the whole operation due to timely maintenance of selective al-adrenoreceptor blockade.

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RU 2 371 178 C1

Authors

Bel'Tsevich Dmitrij Germanovich

Kuznetsov Nikolaj Sergeevich

Lysenko Mar'Jana Anatol'Evna

Kats Ljubov' Efimovna

Kalmykov Aleksandr Vladimirovich

Vanushko Vladimir Ehduardovich

Dates

2009-10-27Published

2008-03-28Filed