FIELD: chemistry.
SUBSTANCE: invention relates to versions of the method of producing chiral non-racemic compound of formula I where R1 represents . Values of the rest of the radicals are given in the formula of invention. Formula I compound is obtained in several steps. The starting material used is cis-1,3-cyclohexanediol. One of the key steps is enzymatic formation of ester or enzymatic splitting of ester.
EFFECT: method is described for production of enantiomeric forms of derivatives of 1,3-cyclohexanedio in cis orientation.
8 cl, 80 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF PRODUCING DIARYL CYCLOALKYL DERIVATIVES | 2005 |
|
RU2414459C2 |
DIARYLCYCLOALKYL DERIVATIVES, METHOD OF THEIR OBTAINING, AND APPLICATION AS PPAR-ACTIVATORS | 2002 |
|
RU2330846C2 |
COMPOUNDS | 2016 |
|
RU2725616C2 |
COMPOUNDS, COMPOSITIONS AND METHODS FOR INCREASING CFTR ACTIVITY | 2015 |
|
RU2767460C2 |
SECONDARY AMINES AS RENIN INHIBITORS | 2007 |
|
RU2425032C2 |
OXAZOLE DERIVATIVES SUBSTITUTED WITH CARBOXYLIC ACIDS AS PPAR-ALPHA AND PPAR-GAMMA ACTIVATORS IN DIABETES TREATMENT | 2002 |
|
RU2278859C2 |
3-CARBONYLAMINO-5-CYCLOPENTYL-1H-PYRAZOLE COMPOUNDS WITH CDK2 INHIBITOR ACTIVITY | 2020 |
|
RU2797889C2 |
HETEROCYCLIC JANUS KINASE 3 INHIBITORS | 2006 |
|
RU2434013C2 |
N-(2-CYANO HETEROCYCLYL)PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | 2014 |
|
RU2669922C2 |
DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES AND RESPIRATORY WAYS DISEASES | 2001 |
|
RU2265011C2 |
Authors
Dates
2009-11-10—Published
2004-02-19—Filed