SALT, PRODUCED FROM AMINE AND CARBOSTYRIL DERIVATIVE Russian patent published in 2009 - IPC C07D215/227 A61K31/4704 A61P1/04 A61P27/02 A61P1/16 A61P29/00 

Abstract RU 2372336 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a salt of amine with carbostyril derivative, formed from carbostyril derivative, with formula , R is a halogen atom, substitution position in the side chain is the 3rd or 4th position in the carbostyril skeleton, and the bond between the 3rd and 4th positions on the carbostyril skeleton is a single or double bond, and amine, chosen from: amino acid; C1-6alkyl-substituted amine, which can have a substituted chosen from a group which contains a hydroxy group and an amino group; and amino sugar, which dissolves in water very well. The invention also relates to a pharmaceutical composition which contains a salt of amine with carbostyril derivative of formula (I) as an active ingredient.

EFFECT: new salts are obtained, with useful biological properties.

25 cl, 13 ex

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RU 2 372 336 C2

Authors

Nisioka Josikhiro

Aki Sindzi

Fudzita Sigekazu

Onisi Josinao

Sumida Sun-Itiro

Dates

2009-11-10Published

2005-01-20Filed