FIELD: chemistry.
SUBSTANCE: method involves alkylation of 7-potassium salt of 3-methylxanthine with 1,4-dibromobutane, with subsequent reaction of the formed 7-(4-bromobutyl)-3-methylxanthane with 1-benzhydrylpiperazine and neutralisation of the obtained base 7-/4-(4-benzhydrylpiperazinyl-1)butyl/-3-methylxanthane with organic or inorganic acid.
EFFECT: obtained compounds have better pharmacotherapeutic properties than current antihistaminic drugs.
2 cl, 1 dwg, 2 ex
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RU2834474C2 |
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RU2111958C1 |
