METHOD OF EARLY DIAGNOSTICS OF GASTROESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH OBESITY Russian patent published in 2009 - IPC A61B10/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is intended for early diagnostics of gastroesophageal reflux disease in patients with obesity. During morphologic examination detected is presence of dystrophic changes of esophagus epithelium in form of hyperkeratosis with nidal cornification and dystrophic changes of epithelial cells with occurrence of cytolysis, formation of layer structures in absence of vascular and immune reaction. During analysis of electromotive activity of cardial part of stomach frequency and amplitude of slow waves are determined and if their frequency increases from 7.5 per min and higher and if amplitude increases from 0.35 mV and higher, presence of early stage of gastroesophageal reflux disease in patients with obesity is diagnosed.

EFFECT: method allows to carry out early diagnostics of gastroesophageal reflux disease in patients with obesity, combining morphologic examination of esophagus epithelium and analysis of electromotive activity of cardial part of stomach.

2 ex, 4 tbl