FIELD: chemistry.
SUBSTANCE: invention relates to biotechnology, specifically to obtaining biologically active substances of peptide nature, with stem cell factor CSF activity towards thymocyte differentiation, and can be used in medicine. An oligopeptide with formula I is obtained through in silico design: A-X1-X2-X3-X4-X5-B (I), where A is Ac; X1 is K or R; X2 is A or G; X3 is S or T; X4 is A, or G, or is absent, X5 is N, or Q, or is absent and B is Ome.
EFFECT: invention allows for obtaining an oligopeptide with stem cell factor CSF activity towards differentiation of immature precursors of T-lymphocytes, and widening the range of effective therapeutic agents for treating myelodysplastic syndrome.
5 dwg, 2 ex
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