DERIVATIVES OF 2-(HERETO)ARYL-SUBSTITUTED TETRAHYDROQUINOLINES Russian patent published in 2009 - IPC C07D401/04 C07D493/04 A61K31/47 A61P43/00 A61P35/00 

Abstract RU 2375354 C2

FIELD: medicine.

SUBSTANCE: there are presented compounds of formula I wherein W, R, R1, R2, R3, R4, R5, R6 and R7 have values specified in cl. 1 of the patent claim, and to method for making these compounds, a based medicinal agent used for treating conditions affected by inhibition, regulation and/or modulation of mitotic motor protein Eg5, to a mixture and application of said compounds for making the medicinal agent.

EFFECT: there are produced and described new compounds which can find application in treating tumours.

40 cl, 654 ex, 3 tbl, 25 dwg

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RU 2 375 354 C2

Authors

Kaj Shimann

Ul'Rikh Ehmde

Dirk Finzinger

Iogannes Glajtts

Khel'Mut Rojbol'D

Frank Tsenke

Dates

2009-12-10Published

2004-12-14Filed