Patenton — panteon of patents

(19)

RU

(11)

2 384 571

(13)

C2

(51)

IPC

C07D209/00(2006-01-01)

C07D221/00(2006-01-01)

C07D471/04(2006-01-01)

C07D519/00(2006-01-01)

A61K31/4745(2006-01-01)

A61K31/498(2006-01-01)

A61K31/541(2006-01-01)

A61P1/00(2006-01-01)

A61P11/00(2006-01-01)

A61P13/00(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2006141842/04, 2005-04-28

(24)

Start date

2005-04-28

(22)

Actual filing date

2005-04-28

(45)

Published

2010-03-20

(72)

Inventor

Kadzino MasakhiroKherd Nikolas Uill'JamTarui NaokiBanno KhirosiKavano JasukhikoInatomi Nobukhiro

(73)

Holder

Takeda Farmas'Jutikal Kompani Limited

CONDENSED QUINOLINE DERIVATIVE AND USE THEREOF Russian patent published in 2010 - IPC C07D209/00 C07D221/00 C07D471/04 C07D519/00 A61K31/4745 A61K31/498 A61K31/541 A61P1/00 A61P11/00 A61P13/00 A61P25/00 

Abstract RU 2384571 C2

FIELD: chemistry.

SUBSTANCE: new compounds have formula (I) , where values of radicals R1 - R10 are as given in paragraph 1 of the formula of invention; n equals 2 or 3, --- denotes absence of substitution or a single bond; and denotes a single bond or a double bond, or to salts thereof. The invention also relates to a method of producing compounds of formula (Ic), to a NK2 receptor antagonist, to a pharmaceutical agent, to a method of antagonising the NK2 receptor, to a method of preventing or treating functional gastrointestinal diseases, as well as to use of compounds given in paragraph 1.

EFFECT: obtaining new biologically active compounds with antagonistic effect on the NK2 receptor.

31 cl, 331 ex, 7 tbl

Similar patents RU2384571C2

Title Year Author Number
SHIP1 MODULATORS AND METHODS RELATED THERETO 2014
  • Makkenzi Llojd F.
  • Makruri Tomas B.
  • Kharvig Kertis
  • Bogutski Devid
  • Rejmond Dzheffri R.
  • Pettigryu Dzheremi D.
 RU2679805C2
TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS 2012
  • Khayasi Keisi
  • Vatanabe Tsuneo
  • Toyama Kodzi
  • Kamon Dzundzi
  • Minami Masataka
  • Uni Miyuki
  • Nasu Mariko
 RU2632870C2
SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS 2011
  • Olkhava Edvard Dzhejms
  • Chesuort Richard
  • Kuntts Kevin Uejn
  • Richon Viktoriya Mari
  • Pollok Roj Makfarlejn
  • Dejgl Skott Richard
 RU2606514C2
RMT5 INHIBITORS 2019
  • Mashasek, Mishell
  • Vitter, Devid
  • Zhibo, Krejg
  • Khuan, Chunkhoj
  • Kavamura, Sukhei
  • Sloman, Devid, L.
  • Silipkhaivankh, Pkhieng
  • Kiros, Rajan
  • Van, Myurrej
  • Shnajder, Sebastyan
  • Jeung, Charlz, S.
  • Rojtershan, Majkl, Kh.
  • Khenderson, Timoti, Dzh.
  • Paparen, Zhan-Loran
  • Raali, Usin
  • Khyuz, Dzhonatan, M., E.
  • Sanyal, Sulagna
  • Je, Jingchun
  • Kandito, Devid, A.
  • Fajer, Patrik, S.
  • Silverman, Stiven, M.
 RU2814198C2
TRICYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USING THEM FOR TREATING IMMUNOLOGICAL AND ONCOLOGICAL COMPOUNDS 2009
  • Uishart Nejl
  • Ardzhiriadi Mariya A.
  • Koldervud Devid Dzh.
  • Eriksson Anna M.
  • Fiamengo Brajan A.
  • Frenk Kristin E.
  • Fridman Majkl
  • Dzhordzh Don M.
  • Godken Erik R.
  • Dzhozefson Natan S.
  • Li Bitsin S.
  • Morytko Majkl Dzh.
  • Styuart Kent D.
  • Voss Dzheffri V.
  • Uollejs Grir A.
  • Van Lu
  • Voller Kevin R.
 RU2545023C9
SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE DERIVATIVES OF PYRIMIDINES, COMPOSITIONS THEREOF AND METHODS OF TREATING USE THEREOF 2012
  • Delgado, Mercedes
  • Yoon, Won, Hyung
  • Tikhe, Jayashree
  • Satoh, Yoshitaka
  • Romanow, William, J.
  • Sloss, Marianne
  • Paisner, David, A.
  • Norris, Stephen
  • Nagy, Mark, A.
  • Moghaddam, Mehran, F.
  • Mccarrick, Meg
  • Lebrun, Laurie, Ann
  • Hilgraf, Robert
  • Erdman, Paul
  • Elsner, Jan
  • Bennett, Brydon, L.
 RU2697712C2
MACROCYCLIC HEPATITIS TYPE C VIRUS INHIBITORS 2006
  • Vekhling Khorst
  • Samuehl'Sson Bertil'
 RU2419619C2
SUBSTITUTED CHROMANS 2015
  • Kim Filip R.
  • Van Syutsin
  • Sirl Kseniya B.
  • Lyu Bo
  • Eung Min S.
  • Altenbech Robert Dzh.
  • Vojt Erik
  • Bogdan Endryu
  • Kenig Dzhon R.
  • Greszler Stiven N.
 RU2718060C2
5-HT RECEPTOR MODULATORS AND METHODS FOR USING THEM 2010
  • Uehlch Denni S.
  • Akritopoulou-Zanze Irini
  • Braje Vil'Frid
  • D'Jurik Stiven V
  • Uilson Noehl' S.
  • Terner Shon K
  • Krudzher Al'Bert V.
  • Relo Ana-Ljusija
  • Shekkhar Shashank
  • Chzhao Khunjuj
  • Gandarilla Khorkhe
  • Gasiki Alan F.
  • Li Khuan'Tsju
  • Tompson Kristina M.
  • Chzhan Min'
 RU2542103C2
PYRROLE DERIVATIVES AS MEDICINAL SUBSTANCES 2005
  • Kanne Bannen Linn
  • Chen Dzheff
  • Dehlrimpl Liza Ehster
  • Flehtt Brenton T.
  • Forsajt Timoti Patrik
  • Gu Sjao-Khoj
  • Mehk Morrison B.
  • Mann Larri U.
  • Mann Grejs
  • Martin Richard
  • Mokhan Radzhu
  • Merfi Brehtt
  • Najman Majkl Charl'Z
  • Stivens Uill'Jam K. Ml.
  • Van Te-Lin'
  • Van Jun
  • Vu Dzhejson Kh.
 RU2470916C2

RU 2 384 571 C2

Authors

Kadzino Masakhiro

Kherd Nikolas Uill'Jam

Tarui Naoki

Banno Khirosi

Kavano Jasukhiko

Inatomi Nobukhiro

Dates

2010-03-20—Published

2005-04-28—Filed

download Download PDF read Similar patents