CONDENSED QUINOLINE DERIVATIVE AND USE THEREOF Russian patent published in 2010 - IPC C07D209/00 C07D221/00 C07D471/04 C07D519/00 A61K31/4745 A61K31/498 A61K31/541 A61P1/00 A61P11/00 A61P13/00 A61P25/00 

Abstract RU 2384571 C2

FIELD: chemistry.

SUBSTANCE: new compounds have formula (I) , where values of radicals R1 - R10 are as given in paragraph 1 of the formula of invention; n equals 2 or 3, --- denotes absence of substitution or a single bond; and denotes a single bond or a double bond, or to salts thereof. The invention also relates to a method of producing compounds of formula (Ic), to a NK2 receptor antagonist, to a pharmaceutical agent, to a method of antagonising the NK2 receptor, to a method of preventing or treating functional gastrointestinal diseases, as well as to use of compounds given in paragraph 1.

EFFECT: obtaining new biologically active compounds with antagonistic effect on the NK2 receptor.

31 cl, 331 ex, 7 tbl

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RU 2 384 571 C2

Authors

Kadzino Masakhiro

Kherd Nikolas Uill'Jam

Tarui Naoki

Banno Khirosi

Kavano Jasukhiko

Inatomi Nobukhiro

Dates

2010-03-20Published

2005-04-28Filed