FIELD: chemistry.
SUBSTANCE: new compounds have formula (I) , where values of radicals R1 - R10 are as given in paragraph 1 of the formula of invention; n equals 2 or 3, --- denotes absence of substitution or a single bond; and
denotes a single bond or a double bond, or to salts thereof. The invention also relates to a method of producing compounds of formula (Ic), to a NK2 receptor antagonist, to a pharmaceutical agent, to a method of antagonising the NK2 receptor, to a method of preventing or treating functional gastrointestinal diseases, as well as to use of compounds given in paragraph 1.
EFFECT: obtaining new biologically active compounds with antagonistic effect on the NK2 receptor.
31 cl, 331 ex, 7 tbl
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Authors
Dates
2010-03-20—Published
2005-04-28—Filed