FIELD: medicine.
SUBSTANCE: invention refers to new derivatives of pyrrolo[3,2-c]pyridine of general formula (I) 
where R1 represents hydrogen; linear or branched C1-C6alkyl group optionally substituted with one or more substitutes chosen from the group consisting of C1-C5alkoxy, C3-C7cyclalkyl, 1,3-dioxolanyl, cyano, naphtyl, C2-C5alkenyloxy and 2,3-dihydrobenzo[1,4]dioxinyl; C2-C6alkenyl group; C2-C6alkinyl group; or benzyl group optionally substituted with one or more substitutes chosen from the group consisting of halogen, C1-C3alkyl, C1-C3alkoxy, cyano, C1-C3alkoxycarbonyl and trifluoru-C1-C3alkyl, R2 represents linear or branched C1-C6alkyl group, R3 represents hydrogen; linear or branched C1-C6alkyl group optionally substituted with hydroxyl or cyano, and R4 represents 1,2,3,4-tetrahydroisoquinolinic group optionally substituted with one or more halogens or C1-C5alkyls; benzyloxy-group optionally substituted with one or more halogens or C1-C5alkyls; or benzylamino group optionally substituted with halogen, and also to the method for making thereof and the pharmaceutical composition inhibiting proton pump.
EFFECT: there are produced and disclosed new compound with inhibitory action on the proton pump and ability to ensure reversible inhibitory effect of the proton pump.
7 cl, 45 ex, 2 tbl
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