FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to pharmaceutical composition of antibiotic, which contains microgranules covered with capsule, and method of their preparation. Said microgranules contain core, which contains clarithromycin, internal layer of capsule, containing at least one cellulose polymer, which is not a polymer of intestine-soluble capsule, in which average size of particles of said covered with capsule microgranules constitutes from approximately 100 to approximately 650 mcm.
EFFECT: antibiotic compositions are described.
16 cl, 9 ex
