SOLID MEDICINAL FORM FOR ORAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE SUBSTANCES SHOWING UNFAVORABLE ORGANOLEPTIC PROPERTIES Russian patent published in 1997 - IPC

FIELD: pharmacy. SUBSTANCE: solid medicinal form has core with active substance covered with polymeric shell that is soluble at pH = 5 or above. Medicinal form has one or some pharmaceutical acceptable organic acids: fumaric, citric, ascorbic and tartaric ones. Core shell can be made of the following polymers: copolymer of methacrylic acid and methylmethacrylate or ethylmethacrylate, cellulose phthalate acetate, hydroxypropylmethylcellulose phthalate, polyvinyl acetatephthalate, shellac, succinateacetatehydroxypropylmethylcellulose, carboxymethylcellulose, cellulose trimellitate acetate and copolymer of maleic acid with phthalic acid derivative. EFFECT: improved properties of medicinal form. 7 cl, 3 tbl