ERYTHROCYTE RESISTANCE ASSESSMENT METHOD Russian patent published in 2010 - IPC G01N33/49 G01N33/92 G01N33/68 

FIELD: chemistry, biochemistry.

SUBSTANCE: invention refers to medicine, namely to biochemistry, can be used for assessment of state of erythrocytes during medical treatment of patient with somatic diseases. Erythrocyte resistance assessment method involves blood sampling, extraction of erythrocytes and determination of their spectral characteristics; at that, extracted erythrocytes are washed in sodium-potassium buffer. After that, ³¹R-NMR spectra of erythrocyte suspension are taken; there determined is content of 2,3-diphosphoglycerate (2,3-DFG) and inorganic phosphate (IP) in terms of percentage; on the basis of obtained values, there determined by formula P_er=2,3-DFG/IP is energy erythrocyte resistance parametre (P_er), and when this value is less than 4.0, energy erythrocyte resistance is considered to be altered.

EFFECT: invention allows using P_er parametre both for assessment of medical treatment effectiveness and for dynamic control of patient's condition after he/she has been discharged from the hospital.

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