FIELD: medicine.
SUBSTANCE: blood plasma is analysed for cytochrome oxidase activity; concentrations of 2,3-diphosphoglycerate and lactic acid in erythrocytes are evaluated. Then oxygenation coefficient K is calculated by formula: K = (C1+C2):A, where A is plasma cytochrome oxidase activity, mol/l; C1 - concentration of 2,3-diphosphoglycerate in erythrocytes, mol/l; C2 - concentration of lactic acid in erythrocytes, mol/l. If said oxygenation coefficient is more than 1.0, hypoxia is diagnosed.
EFFECT: technique allows improving reliability of hypoxia diagnostics and reducing acquisition time to 4 hours.
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Authors
Dates
2010-04-20—Published
2009-01-27—Filed