SUBSTITUTED HYDANTOINS Russian patent published in 2010 - IPC C07D417/12 C07D417/14 A61K31/427 A61P35/00 

Abstract RU 2383542 C2

FIELD: chemistry.

SUBSTANCE: described are compounds of formula (I)

Values of radicals R1-R6 are given in the formula of invention. The compounds inhibit protein kinase MEK1/2. Also described is a pharmaceutical composition for administration in diseases mediated by MEK1/2.

EFFECT: compounds are highly efficient.

16 cl, 27 ex

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RU 2 383 542 C2

Authors

Chu Sin'Tszi

Fotui Nader

Kh'Jubi Nikolas Dzhon Silvester

Kong Norman

Makdermott Li Apostle

Moliterni Dzhon Antoni

Dzhan Dzhumin

Dates

2010-03-10Published

2005-08-09Filed