SULTAM DERIVATIVES Russian patent published in 2015 - IPC C07D275/06 C07D417/12 A61K31/425 A61P35/00 

FIELD: chemistry.

SUBSTANCE: invention refers to a compound of formula 1, where R₂ represents hydrogen or dimethylaminogroup; R₃ represents hydrogen; R₄ represents C_3-10-cycloalkyl optionally substituted by C_1-6-alkyl, or benzyl optionally substituted by halogen; or R₃ and R₄ together with nitrogen atom, to which they are attached, form piperidinyl substituted by one or more substitutes independently specified in a group consisting of hydroxyl or phenyl optionally substituted by halogen; R₅ represents C_1-6-alkyl or benzyl optionally substituted by halogen; R₆ represents benzodioxolyl or phenyl optionally substituted by 1-3 substitutes independently specified in a group consisting of halogen, hydroxyl, C_1-6-alkoxygroup optionally substituted by halogen, C_1-6-alkyl, phenoxygroup optionally substituted by halogen, cyanogroup or C_1-6-alkyl, and phenyl optionally substituted by C_1-6-alkyl or halogen, or its pharmaceutically acceptable salt. The compound of formula 1 is applicable for producing a composition or a medicinal product for treating or controlling cell proliferative disorders.

EFFECT: sultam derivatives showing cytotoxic activity.

40 cl, 38 ex