PLASMIDS CODING VERSIONS OF PROTEIN p185 SEQUENCE, AND THEIR THERAPEUTIC APPLICATION Russian patent published in 2010 - IPC C12N15/85 C12N15/12 A61K48/00 

FIELD: microbiology.

SUBSTANCE: invention represents plasmid vector for transfer of DNA, which comprises sequence coding various fragments of oncoprotein p185^neu, which are able to induce immune response in respect to tumors, which hyperexpress p185^neu. Invention is also related to pharmaceutical composition on the basis of vector for prophylactics or treatment of patients with risk of development of p185^neu-positive tumors, or patients with primary tumors, metastases or relapses of p185^neu-positive tumors.

EFFECT: invention makes it possible to increase efficiency of prophylactics or treatment of patients with risk of development of p185^neu-positive tumors, or patients with primary tumors, metastases or relapses of p185^neu-positive tumors.

10 cl, 14 dwg, 2 tbl, 2 ex