MONOMOLECULAR CHIMERIC T-CELL RECEPTOR TO CANCER ANTIGEN CA125 Russian patent published in 2021 - IPC C07K16/28 C07K14/725 C12N5/10 C12N15/13 C12N15/63 A61K39/395 A61P35/00 

Abstract RU 2747095 C2

FIELD: immunology.

SUBSTANCE: single-stranded antibody to CA125 tumor specific antigen, a chimeric monomolecular T-cell receptor for tumor-specific CA125 antigen are disclosed. Also, nucleic acid, an expression vector and a host cell are considered.

EFFECT: this invention can find further application in therapy of oncological diseases.

7 cl, 16 dwg, 6 tbl, 3 ex

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RU 2 747 095 C2

Authors

Bozhenko Vladimir Konstantinovich

Kudinova Elena Aleksandrovna

Kulinich Tatyana Mikhajlovna

Kiseleva Yana Yurevna

Shishkin Aleksandr Mikhajlovich

Dates

2021-04-26Published

2018-05-11Filed