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(19)

(11)

2 384 344

(13)

(51)

IPC

A61K38/17(2006-01-01)

C12N15/62(2006-01-01)

A61K31/505(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2007123607/15, 2005-12-02

(24)

Start date

2005-12-02

(22)

Actual filing date

2005-12-02

(45)

Published

2010-03-20

(72)

Inventor

Vrin'O Patris'JaShiron-Blondel' Mariell'Bisseri Mari-KristinFerfajn EhrikKhoulash DzhoslinSedarbaum Dzhess M.

(73)

Holder

Aventis Farma S.A.

ANTICANCER COMPOSITIONS CONTAINING AGENT INHIBITING VEGF AND 5FU OR ONE OF ITS DERIVATIVES Russian patent published in 2010 - IPC A61K38/17 C12N15/62 A61K31/505 A61P35/00

Abstract RU 2384344 C2

FIELD: medicine.

SUBSTANCE: invention represents a combination containing VEGF Trap and 5-fluorouracil to be applied in treatment of neoplasms.

EFFECT: higher effectiveness of the combination ensured by therapeutic synergism of its components, and reduced toxicity.

4 cl, 1 ex, 1 tbl

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RU 2 384 344 C2

Authors

Vrin'O Patris'Ja

Shiron-Blondel' Mariell'

Bisseri Mari-Kristin

Ferfajn Ehrik

Khoulash Dzhoslin

Sedarbaum Dzhess M.

Dates

2010-03-20—Published

2005-12-02—Filed