COMBINATIONS OF ANTI-HER2 ANTIBODY-DRUG CONJUGATE AND CHEMOTHERAPEUTIC AGENTS AND METHODS OF USE Russian patent published in 2018 - IPC A61K31/337 A61K39/395 A61P35/00 

Abstract RU 2671489 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, oncology, and can be used to treat tumors. This method comprises administering a therapeutic combination comprising a therapeutically effective amount of trastuzumab-MCC-DM1 and a therapeutically effective amount of pertuzumab as a combined composition or alternately to a mammal.

EFFECT: use of the invention makes it possible to treat tumors due to the synergistic effect of the combination.

11 cl, 22 tbl, 37 dwg, 5 ex

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RU 2 671 489 C2

Authors

Berri Linn

Fillips Gejl Lyuis

Slivkovski Mark Ks.

Dates

2018-11-01Published

2013-10-24Filed