CHOLESTEROL-CONTAINING COMPOUNDS AND APPLICATION THEREOF AS BORRELIA BURGDORFERI IMMUNOGENS Russian patent published in 2010 - IPC C07J9/00 A61K31/575 A61P37/00 A61P31/04 

Abstract RU 2385323 C2

FIELD: medicine.

SUBSTANCE: invention is related to cholesterol-6-O-acyl-β-D-galactopyranoside intended for inducing in a host mammal of immune reaction on B.burgdorferi, where (i) residual acyl represents a group recovered from organic fatty acids containing 1-25 carbon atoms; (ii) galactopyranoside ring structure optionally contains acyl group recovered from fatty acid in any position of the ring. The invention also covers mixed 3-O-(6-O-palmitoyl-(β-D-galactopyranosyl)-cholesterol and 3-O-(6-O-oleoyl-β-D-galactopyranosyl)cholesterol intended for inducing in a host mammal of immune reaction on B.Burgdorferi.

EFFECT: compounds are especially effective for prevention or treatment of Lim's disease.

7 cl, 4 tbl, 15 dwg, 15 ex

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RU 2 385 323 C2

Authors

Ben-Menakhem Dzhil

Kubler-Kelb Ioanna

Shneerson Rejchel

Robbins Dzhon B.

Pozhsgaj Vins

Dates

2010-03-27Published

2004-04-02Filed