NONINHALATION NARCOSIS TECHNIQUE IN EXPERIMENT Russian patent published in 2010 - IPC A61K31/05 A61K31/135 A61K31/551 A61P23/00 A61M16/04 

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely experimental surgery, and can be used as an anaesthesia care in experimental operative interventions. That is ensured by initial narcosis by intramuscular introduction in the same syringe of a combination of preparations, including ketamine in a dose 1.0-1.5 ml per 3-4 kg of an animal's body weight and rometar in a dose 2.0-4.9 ml per 3-4 kg of the animal's body weight. After 4-5 minutes following the initial narcosis, pofol is administered intravenously in a dose 1.0-3.0 ml per 3-4 kg of the animal's body weight; then 1-7 minutes later, intubation follows that includes the second administration of pofol in a dose 0.2-0.3 ml regardless the animal's body weight. The following injections of pofol to maintain anaesthesia are carried out in the beginning of each hour of the operative intervention with considering its duration in a dose 1.0 ml regardless the animal's body weight.

EFFECT: method ensures the optimal conditions to prepare the animal for the noninhalation anaesthesia due to preliminary combined intramuscular introduction of rometar and ketamine, and also maintained adequate anaesthesia with low doses of the administered preparations owing to their potentiation interactions.

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