METHOD FOR SYNTHESIS OF 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND Russian patent published in 2010 - IPC C07D231/20 C07D231/22 C07D413/12 

Abstract RU 2386619 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method for synthesis of a 5-hydroxy-4-thiomethylpyrazole compound, where a pyrazole compound of general formula is reacted with a sulphur compound of general formula X-S(O)n-R (2) in the presence of a base and formaldehyde to form a 5-hydroxy-4-thiomethyl compound of general formula , where radicals and symbols in the said formulae are defined in the formula of invention.

EFFECT: easier synthesis of the desired 5-hydroxy-4-thiomethylpyrazole compound with high output in mild conditions in a single step without using special equipment, expensive catalyst or a transition metal etc, where the process can be carried out virtually without formation of hazardous wastes from a catalyst etc; owing to this, the method is environmentally safe and can be used in industry.

6 cl, 16 ex

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RU 2 386 619 C2

Authors

Utida Jukio

Dates

2010-04-20Published

2005-03-31Filed