HETEROCYCLIC COMPOUNDS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF Russian patent published in 2018 - IPC C07D409/12 C07D409/14 C07D413/12 C07D417/04 C07D417/12 C07D495/04 A61K31/496 A61K31/4709 A61K31/517 A61K31/519 A61K31/538 A61K31/5415 A61P25/00 

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof:

in which A is C, B and D are each independently C or N; is a single or double bond; R₁ is hydrogen or 1–4 substituents, each of which is independently selected from the group consisting of halogen, hydroxy, oxo (=O), C1~C6 alkoxy, C1~C6 alkylthio, C1~C6 alkyl, cyano, carbamoyl (-CONH₂), C1~C6 alkyl substituted carbamoyl; R₂ is absent or denotes 1 to 3 substituents, each of which is independently selected from the group consisting of halogen, hydroxy, C1~C6 alkoxy, C1~C6 alkylthio, C1~C6 alkyl, carbamoyl (-CONH₂), C1~C6 alkyl substituted carbamoyl; R₃ is hydrogen or 1-4 substituents, each of which is independently selected from the group consisting of hydroxyl and C1~C6 alkyl groups; L is absent or denotes C1~C5 alkylene, and when L is C1~C5 alkylene, the alkylene is optionally substituted with one or more substituents selected from the group consisting of hydroxy, C1~C6 alkoxy and oxo (=O) groups; ring G is a heterobicyclic group, wherein said heterobicyclic group is a heteromonocyclic group bonded to a phenyl or a heteromonocyclic group bonded to a heteromonocycle, and said heteromonocyclic group contains at least one heteroatom selected from the group consisting of N, S and O; ring G is bonded to L via a carbon atom on ring G; and ring G is arbitrarily substituted with one or more substituents.

EFFECT: prevention and/or treatment of diseases of the central nervous system.

20 cl, 3 tbl, 56 ex