PHARMACEUTICAL SALTS OF 3-O-(3',3-DIMETHYLSUCCINYL) BETULINIC ACID Russian patent published in 2010 - IPC C07J53/00 C07J63/00 A61K31/56 A61P31/18 

Abstract RU 2387665 C2

FIELD: medicine.

SUBSTANCE: there are described salts of 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB). Particularly, there is disclosed production process, pharmaceutical estimation and bioavailability estimation in vivo of N-methyl-D-glucamine salt and alkali salt. The pharmaceutical compositions containing these salt forms are used in methods of treating HIV infection and related diseases. There is also described method for preparing DBS salts.

EFFECT: improved clinical effectiveness.

12 cl, 5 ex, 5 tbl

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RU 2 387 665 C2

Authors

Pauehr Martin Dejl

Martin Dehvid Judzhin

Dates

2010-04-27Published

2005-03-17Filed