FIELD: medicine.
SUBSTANCE: formulation is adapted for introduction to a subject by dispersing with any known spray; said formulation can be included in a kit. The formulation is introduced in the form of an aqueous solution; however it can be stored as a dry powder, a prepared solution or a concentrated composition. The formulation is used in advanced spray system for corticosteroid inhalation. SAE-γCD found in the formulation considerably improves chemical stability of budesonide. There is described a method for inhalation of the formulation. The formulation can be also administered by a common intranasal apparatus. The formulation can contain one or more additional therapeutic agents to be used in combinations with said corticosteroid. SAE-γCD is especially effective for solubilisation of etherified corticosteroids.
EFFECT: development of the inhalation formulation containing SAE-γCD and said corticosteroid.
27 cl, 2 tbl, 5 dwg, 20 ex
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