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2 388 066

(13)

(51)

IPC

G09B23/28(2006-01-01)

A61K31/197(2006-01-01)

A61P1/04(2006-01-01)

(21) (22)

Application

2008131632/14, 2008-08-01

(24)

Start date

2008-08-01

(22)

Actual filing date

2008-08-01

(45)

Published

2010-04-27

(72)

Inventor

Lazebnik Leonid BorisovichLychkova Alla EhduardovnaVasil'Ev Jurij Vasil'EvichJanova Oksana Borisovna

(73)

Holder

Lazebnik Leonid BorisovichLychkova Alla EhduardovnaVasil'Ev Jurij Vasil'EvichJanova Oksana Borisovna

METHOD FOR PREVENTION OF GASTROESOPHAGEAL REFLUX Russian patent published in 2010 - IPC G09B23/28 A61K31/197 A61P1/04

Abstract RU 2388066 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental pharmacology and gastroenterology and concerns prevention of gastroesophageal reflux in experiment. Gastroesophageal reflux is modelled by single introduction of methylene blue into an animal's cardiac orifice. The preliminary introduction of the preparation L-NAME in a dose 1-5 mg/kg inhibits the development of gastroesophageal reflux.

EFFECT: method prevents the development of gastroesophageal reflux in experiment within a week after the single introduction of L-NAME in said dosage range.

3 ex

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RU 2 388 066 C1

Authors

Lazebnik Leonid Borisovich

Lychkova Alla Ehduardovna

Vasil'Ev Jurij Vasil'Evich

Janova Oksana Borisovna

Dates

2010-04-27—Published

2008-08-01—Filed