FIELD: chemistry.
SUBSTANCE: invention relates to an improved method of obtaining a mixture of trifluoroacetyl-glatiramer acetate, where the obtained mixture of polypeptides contains not more than 0.1% brominated tyrosine and less than 1000 parts/million metal ion impurities.
EFFECT: design of an improved method of obtaining a mixture of trifluoroacetyl-glatiramer acetate.
20 cl, 1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COPOLYMER-1, METHODS FOR PRODUCTION THEREOF AND ANALYTICAL METHODS | 2012 |
|
RU2604521C2 |
| METHOD OF PREPARING POLYPEPDITE MIXTURES USING HYDROGENOLYSIS | 2006 |
|
RU2419638C2 |
| PEPTIDE COPOLYMER, SYNTHESIS METHOD THEREOF AND PHARMACEUTICAL COMPOSITION BASED ON SAID COPOLYMER | 2009 |
|
RU2402576C1 |
| IMPROVED COPOLYMER-1 IN COPOLYMER COMPOSITION | 1995 |
|
RU2161489C2 |
| IMPROVED COPOLYMER-1 AND METHOD OF PREPARATION THEREOF | 1995 |
|
RU2198900C2 |
| VACCINE AND METHOD FOR TREATING MOTOR NEURON DISEASES | 2002 |
|
RU2303996C2 |
| COP1 FOR TREATMENT OF INFLAMMATORY DISEASES OF INTESTINE | 2004 |
|
RU2339397C2 |
| METHOD FOR OBTAINING GLATIRAMER ACETATE PRODUCT | 2015 |
|
RU2669769C2 |
| METHODS OF DISEASE TREATMENT BY MEANS OF STATISTICAL COPOLYMERS | 2005 |
|
RU2410115C2 |
| METHODS FOR PURIFYING ANTIBODIES | 2014 |
|
RU2651483C2 |
