FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to veterinary science and concerns applications of protein ORF-2 of porcine circovirus 2 for making a vaccine for protection of piglets from PCV-2 infection with positive maternal antibodies (MDA-positive). A minimal dose 20 mcg/dose of protein ORF-2 of porcine circovirus 2 (PCV-2) is able to induce a protective immune response to PCV-2 even if they have relatively high MDA titre to PCV-2. The vaccine under the invention can contain recombinant protein ORF-2 where said recombinant protein is preferentially prepared by expression in baculovirus express ion vector in insects cells, said baculovirus express ion vector contains sequence of gene ORF-2 PCV-2 under control of p10 promotor.
EFFECT: ensured protection against infection in MDA-positive piglets.
9 cl, 5 ex, 2 tbl
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