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2 391 047

(13)

(51)

IPC

A61B5/55(2006-01-01)

A61K49/06(2006-01-01)

(21) (22)

Application

2007118383/14, 2005-11-18

(24)

Start date

2005-11-18

(22)

Actual filing date

2005-11-18

(45)

Published

2010-06-10

(72)

Inventor

Lerke Matil'DeZandt ReneGol'Man KlaehsTaning Mikkel'Ardenk'Jaehr-Larsen Jan-KhenrikPetersson Stefan

(73)

Holder

Dzhi-I Kheltker As

WAY OF VISUALISATION OF HEART USING HYPERPOLARISED C-PYRUVATE Russian patent published in 2010 - IPC A61B5/55 A61K49/06

Abstract RU 2391047 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine and is designed to evaluate the viability of myocardial tissue. Direct ¹³C-MR images of ¹³C-pyruvate and its ¹³C-containing metabolites of alanine, lactate and possibly bicarbonate in a subject, who the composition containing hyperpolarised ¹³C-pyruvate is administered beforehead. Correlation of ¹³C signal of metabolite with ¹³C signal of any other metabolite detected is conducted for acquisition the contrast based on the difference of signals intensity of two, preferably three, most preferably four ¹³C metabolites.

EFFECT: method allows to identify at-risk myocardial tissue.

13 cl, 5 ex, 2 dwg

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RU 2 391 047 C2

Authors

Lerke Matil'De

Zandt Rene

Gol'Man Klaehs

Taning Mikkel'

Ardenk'Jaehr-Larsen Jan-Khenrik

Petersson Stefan

Dates

2010-06-10—Published

2005-11-18—Filed