METHOD OF BLOCKING SIGNAL PATH ACTIVATED BY TGF-beta FACTOR OF VgI IN ANIMAL CELLS Russian patent published in 2010 - IPC C07K14/475 G01N33/68 

Abstract RU 2391352 C1

FIELD: chemistry; biochemistry.

SUBSTANCE: invention relates to molecular biology, specifically to proteins which regulate cell differentiation through inhibition of the TGF-beta cell superfamily. The invention is aimed at treating and preventing diseases related to human VgI orthologs. Noggin2 protein which contains VgI protein is injected into tissue in amount which is efficient for inhibiting VgI activity.

EFFECT: invention enables to solve the task of blocking the signal path activated by the TGF-beta factor of VgI in aniamal cells.

2 dwg, 4 ex

Similar patents RU2391352C1

Title Year Author Number
METHOD OF BLOCKING SINGALLING PATHWAY ACTIVATED BY TGF-beta FACTOR DERRIERE IN ANIMAL CELLS 2009
  • Bajramov Andrej Vjacheslavovich
  • Eroshkin Fedor Mikhajlovich
  • Martynova Natal'Ja Jur'Evna
  • Ermakova Galina Vladimirovna
  • Serebrjakova Marina Valentinovna
  • Solov'Eva Elena Anatol'Evna
  • Zarajskij Andrej Georgievich
RU2407799C1
NOGGIN2-BASED ACTIVIN ACTIVITY BLOCKING METHOD 2005
  • Zarajskij Andrej Georgievich
  • Eroshkin Fedor Mikhajlovich
  • Bajramov Andrej Vjacheslavovich
RU2354662C2
METHOD FOR SIGNAL PATH BLOCKING ACTIVATED BY Wnt8 FACTORS IN ANIMAL CELLS BY MEANS OF NOGGIN FAMILY PROTEINS 2011
  • Bajramov Andrej Vjacheslavovich
  • Eroshkin Fedor Mikhajlovich
  • Martynova Natal'Ja Jur'Evna
  • Ermakova Galina Vladimirovna
  • Serebrjakova Marina Valentinovna
  • Solov'Eva Elena Anatol'Evna
  • Zarajskij Andrej Georgievich
RU2473561C1
METHOD FOR PRODUCING POPULATION OF PANCREATIC ENDOCRINE CELLS CO-EXPRESSING NKX6.1 AND INSULIN, AND METHOD OF TREATING DIABETES 2010
  • Xu, Jean
RU2701335C2
DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS 2010
  • Syuj Dzhin
RU2610176C2
DIFFERENTIATION OF HUMAN EMBRYO STEM CELLS 2008
  • Sjuj Dzhin
RU2473685C2
METHOD OF CULTIVATION PLURIPOTENTIAL STEM CELLS 2005
  • Akaike Tosikhiro
  • Fukuda Kejiti
RU2375448C2
DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS 2018
  • Syuj Dzhin
RU2782271C2
DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS 2008
  • Rezania Alireza
RU2465323C2
DIFFERENTIATING HUMAN EMBRYONIC STEM CELLS 2010
  • Sjuj, Dzhin
  • Ensen, Jan
RU2540016C2

RU 2 391 352 C1

Authors

Bajramov Andrej Vjacheslavovich

Eroshkin Fedor Mikhajlovich

Martynova Natal'Ja Jur'Evna

Ermakova Galina Vladimirovna

Serebrjakova Marina Valentinovna

Solov'Eva Elena Anatol'Evna

Zarajskij Andrej Georgievich

Dates

2010-06-10Published

2008-10-24Filed