FIELD: chemistry; biochemistry.
SUBSTANCE: invention relates to biotechnology and can be used in medical industry during production of antibacterial antibiotic lincomycin hydrochloride which is efficient in treating infections caused by gram-positive agents, including methicillin with stable and certain anaerobic bacteria. The method involves culturing a Streptomyces roseolus VKPM S-1082 strain, which is a lincomycin producer, on a culture medium with given composition, extraction of lincomycin with organic solvents from the native solution, extraction of lincomycin with subsequent isolation. The obtained extract is concentrated and crystallised to obtain lincomycin in hydrochloride form.
EFFECT: invention increases output of lincomycin.
2 cl, 1 tbl, 2 ex
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