METHOD OF EVALUATING EFFICIENCY OF CROHN'S DISEASE AND ULCERATIVE COLITIS TREATMENT Russian patent published in 2010 - IPC A61B10/00 G01N33/50 

Abstract RU 2391914 C2

FIELD: medicine.

SUBSTANCE: in order to evaluate efficiency of Crohn's disease and ulcerative colitis treatment, biochemical blood test and examination of electromotor activity of ascending part of large intestine are carried out. Content of IL-1β, immunoglobulins IgM, IgG and IgA, level of autoantibodies to neutrophils and parietal cells in blood serum is determined. If level of IL-1β increases on 45% and higher, IgM - from 1.6 g/l to 2.18 g/l; IgG - from 11.2 to 14.8 g/l, IgA - from 1.42 to 2.84 g/l; level of autoantibodies to neutrophils decreases from 42 to 28 U/ml and to parietal cells - from 38 to 32 U/ml; frequency of slow waves of electromotor activity of ascending part of large intestine decreases from 22 to 15 per minute, amplitude - from 0.32 to 0.2 mV, treatment of Crohn's disease and ulcerative colitis is considered to be efficient.

EFFECT: method increases accuracy of efficiency evaluation in treatment of Crohn's disease and ulcerative colitis.

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Authors

Lazebnik Leonid Borisovich

Konopljanikov Anatolij Georgievich

Ruchkina Irina Nikolaevna

Khomeriki Sergej Germanovich

Rogozina Vera Aleksandrovna

Konopljanikova Ol'Ga Andreevna

Tsaregorodtseva Tamara Mikhajlovna

Parfenov Asfol'D Ivanovich

Knjazev Oleg Vladimirovich

Lychkova Alla Ehduardovna

Dates

2010-06-20Published

2008-08-01Filed