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IPC

A61K35/28(2006-01-01)

A61P1/04(2006-01-01)

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Application

2008113522/14, 2008-04-10

(24)

Start date

2008-04-10

(22)

Actual filing date

2008-04-10

(45)

Published

2009-08-20

(72)

Inventor

Lazebnik Leonid BorisovichKonopljanikov Anatolij GeorgievichKnjazev Oleg VladimirovichParfenov Asfol'D IvanovichKonopljanikova Ol'Ga AndreevnaRuchkina Irina Nikolaevna

(73)

Holder

Lazebnik Leonid BorisovichKonopljanikov Anatolij GeorgievichKnjazev Oleg VladimirovichParfenov Asfol'D IvanovichKonopljanikova Ol'Ga AndreevnaRuchkina Irina Nikolaevna

THERAPY OF INFLAMMATORY BOWEL DISEASES Russian patent published in 2009 - IPC A61K35/28 A61P1/04

Abstract RU 2364405 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to gastroenterology, and concerns therapy of inflammatory bowel diseases that is ensured by intravenous introduction of allogenerated mesenchymal stem human bone marrow cells in a dose 1.5-2.0·10¹¹ cells dissolved in physiologic saline 200 ml within 3-4 hours. Administered therapy is considered to be effective, if ferritin "ФНОα" is decreased twice and more and IL-4 is increased in 1.5 times and more, while C-reactive protein is decreased 40 to 21 mkmmol/l.

EFFECT: method allows for therapy of inflammatory bowel diseases under the control of objective indicators of therapeutic effectiveness without application of pharmacological preparations and manifestation of their adverse reaction.

3 ex

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RU 2 364 405 C1

Authors

Lazebnik Leonid Borisovich

Konopljanikov Anatolij Georgievich

Knjazev Oleg Vladimirovich

Parfenov Asfol'D Ivanovich

Konopljanikova Ol'Ga Andreevna

Ruchkina Irina Nikolaevna

Dates

2009-08-20—Published

2008-04-10—Filed