FIELD: chemistry.
SUBSTANCE: invention relates to 3,3-diphenylpropylamino monoesters in form of highly pure bases, particularly to (R)-2-[3-(1,1-diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenylisobutyrate (fesoterodine), to their preparation and use as medicinal agents for transdermal and transmucous administration.
EFFECT: obtaining a product which contains (R)-2-[3-(1,1-diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenylisobutyrate (fesoterodine) as a free base containing less than 3 wt % salt with degree of purity of over 97 wt %.
17 cl, 4 dwg, 4 tbl, 5 ex
