METHOD OF PHOTODYNAMIC HEALING OF SEPTIC WOUNDS AND TROPHIC ULCERS Russian patent published in 2010 - IPC A61N5/67 A61B5/00 A61K31/195 A61P17/02 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used for photodynamic healing of septic wounds and trophic ulcers. That is ensured by measuring fluorescence spectra of endogenic porphyrins in the affected region and healthy skin and estimating their concentration. The concentrations of porphyrins in the affected region and healthy skin are compared. 5-ALK is used on the affections with the concentration under the therapeutic value. It is followed with measuring fluorescence spectra of 5-ALK-induced protoporphyrin IX and estimating its accumulation. Then the affected region is irradiated at wave length 630±10 nm and power density 30-100 J/cm². The irradiation procedure is controlled by measuring fluorescence spectra. The irradiation is stopped when observing weakening of ALK-induced protoporphyrin IX under the therapeutic value.

EFFECT: method allows improving clinical effectiveness in healing the septic wounds and trophic ulcers, including long-term, due to the use of proper porphyrins as photosensitisers, estimation of 5-ALK-induced protoporphyrin IX accumulation and control of the concentration of 5-ALK-induced protoporphyrin IX during the irradiation procedure.

5 cl, 3 dwg, 3 ex